What is Pre Breakfast Hyperglycemia and Honeymoon period?

Somogyi Effect :

In some diabetics there will be increase in blood glucose levels in the early morning due to Somogyi effect. Somogyi effect is due to a surge of counter regulatory hormones to produce high glucose levels. Another reason is waning of circulatory insulin in the early morning.

Pattern of blood glucose levels -
(Ref. to CMDT)

At 10 PM – 90 mg/dl
At 3 AM – 40 mg/dl
At 7 AM – 200 mg/dl

Dawn phenomenon :

Another reason for pre breakfast hyperglycemia is due to reduced tissue sensitivity.

Pattern of blood glucose levels -
(Ref. to CMDT)

At 10 PM – 110 mg/dl
At 3 AM – 110 mg/dl
At 7 AM – 150 mg/dl

Both are diagnosed by glucose monitoring at 3 AM for few days along with regular 7 PM glucose. The dose of insulin is adjusted to prevent this. For example in Dawn phenomenon, dosage of intermediate insulin is divided at dinner time and bed time.

Honeymoon period :

This is generally seen in Type 1 diabetes. There is an initial period of ketoacidosis followed by symptom free interval (honeymoon period). Due to stress induced epinephrine blocks insulin secretion. No treatment as such is required for it.

[tags]hyperglycemia, somogyi, diabetes, diabetic[/tags]